{"id":64387,"date":"2025-12-01T01:05:14","date_gmt":"2025-11-30T20:05:14","guid":{"rendered":"https:\/\/www.royalclinicdubai.com\/?p=64387"},"modified":"2026-02-25T11:27:14","modified_gmt":"2026-02-25T06:27:14","slug":"is-clomipramine-still-used-for-ocd","status":"publish","type":"post","link":"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/","title":{"rendered":"Is clomipramine still used for OCD?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Are you struggling with the overwhelming and intrusive thoughts? Do you want to consider clomipramine, but are afraid of it as being an old medicine? You would be thinking; <\/span><b>Is clomipramine still used for OCD? <\/b><span style=\"font-weight: 400;\">Don\u2019t worry, this blog will explain how it still has a vital role to alleviate the symptoms of obsessive-compulsive disorder. Let&#8217;s explore the subject in detail!<\/span><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-transparent ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Obsessive-Compulsive_Disorder\" >Obsessive-Compulsive Disorder<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Is_clomipramine_still_used_for_OCD\" >Is clomipramine still used for OCD?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Affects_Neurotransmitters\" >Affects Neurotransmitters<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Boosts_serotonin_Levels\" >Boosts serotonin Levels<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Calms_down_the_OCD_Loops\" >Calms down the OCD Loops<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Induce_a_balanced_emotional_response\" >Induce a balanced emotional response<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Restore_Peace_of_Mind_with_Clomipramine-Book_Us_Now\" >Restore Peace of Mind with Clomipramine-Book Us Now!<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#FAQs\" >FAQs!<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Is_clomipramine_still_used_for_OCD-2\" >Is clomipramine still used for OCD?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#How_does_clomipramine_treat_Obsessive-Compulsive_Disorder\" >How does clomipramine treat Obsessive-Compulsive Disorder?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Is_clomipramine_more_effective_than_SSRIs\" >Is clomipramine more effective than SSRIs?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#When_are_the_effects_of_clomipramine_for_OCD_felt\" >When are the effects of clomipramine for OCD felt?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/is-clomipramine-still-used-for-ocd\/#Why_is_clomipramine_not_the_first_choice_for_OCD\" >Why is clomipramine not the first choice for OCD?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Obsessive-Compulsive_Disorder\"><\/span><span style=\"font-weight: 400;\">Obsessive-Compulsive Disorder<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><b>Obsessive-Compulsive Disorder<\/b><span style=\"font-weight: 400;\"> is a medical condition characterized by the occurrence of Obsessions and compulsions. Obsessions are the unwanted images in the mind that cause anxiety or depression. Compulsion is a repetitive attitude or mental acts carried out to lessen the effects of obsessions. Thanks to the modern medical field, which has brought many treatments for it, such as clomipramine medicines.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Is_clomipramine_still_used_for_OCD\"><\/span><span style=\"font-weight: 400;\">Is clomipramine still used for OCD?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Yes, clomipramine is an FDA-approved medicine that is used to manage Obsessive-Compulsive Disorder. Although it is an old medicine, it has not lost its effectiveness with the discovery of modern medicines. Clomipramine still works as a frontline for this treatment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here is how clomipramine works for OCD to ensure peace of mind:<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Affects_Neurotransmitters\"><\/span><span style=\"font-weight: 400;\">Affects Neurotransmitters<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Contrary to other medicines like SSRIs. Clomipramine gently affects norepinephrine and dopamine. These neurotransmitters are responsible for the production of obsessions and compulsions during OCD. By relaxing these, clomipramine helps relieve OCD.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Boosts_serotonin_Levels\"><\/span><span style=\"font-weight: 400;\">Boosts serotonin Levels<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Clomipramine is a tricyclic antidepressant (TCA) that works similarly to modern SSRIs. Clomipramine supports the functioning of serotonin and\u00a0 increases serotonin activities\u00a0 in the brain and which helps:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lowers repetitive thoughts and emotions.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduces the desire to perform compulsions.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Minimizes the obsessions linked with depression.<\/span><\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"Calms_down_the_OCD_Loops\"><\/span><span style=\"font-weight: 400;\">Calms down the OCD Loops<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">OCD is caused by the brain circuit consisting of the orbitofrontal cortex, caudate nucleus and thalamus.\u00a0 Clomipramine medicines minimize the hyperactive signaling in their loop. Thus, breaking their cooperation during the obsessions and compulsions. In this manner, this medication stabilizes the neurotransmission.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Induce_a_balanced_emotional_response\"><\/span><span style=\"font-weight: 400;\">Induce a balanced emotional response<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People suffering from OCD often face intense emotions such as guilt, fear, and depression due to the obsessive thoughts. Clomipramine minimizes these extensive emotions, neutralizes thoughts, and enhances the overall mood functioning.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">With the balance of such emotions and thoughts, people can easily handle compulsions and keep themselves busy in therapy.<\/span><\/p>\n<h4><span class=\"ez-toc-section\" id=\"Restore_Peace_of_Mind_with_Clomipramine-Book_Us_Now\"><\/span><span style=\"font-weight: 400;\">Restore Peace of Mind with Clomipramine-Book Us Now!<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p><span style=\"font-weight: 400;\">It&#8217;s time to take action towards OCD management and choose the right treatment. Our expert teams at <\/span><a href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/\">Enfield Royal Clinic<\/a><span style=\"font-weight: 400;\"> are ready to provide <a href=\"https:\/\/www.royalclinicdubai.com\/en-ae\/psychiatrist\/ocd-treatment\/\">OCD Treatment<\/a> anytime. They will further explain the query: <\/span><b>Is clomipramine still used for OCD? <\/b><span style=\"font-weight: 400;\">So, without wasting your precious time,\u00a0 reach us quickly by booking an appointment with us now!<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"FAQs\"><\/span><span style=\"font-weight: 400;\">FAQs!<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<style>#sp-ea-64388 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-64388.sp-easy-accordion>.sp-ea-single {margin-bottom: 10px; border: 1px solid #e2e2e2; }#sp-ea-64388.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #444;}#sp-ea-64388.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #fff; color: #444;}#sp-ea-64388.sp-easy-accordion>.sp-ea-single {background: #eee;}#sp-ea-64388.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: left; color: #444;font-size: 16px;}<\/style><div id=\"sp_easy_accordion-1763964393\"><div id=\"sp-ea-64388\" class=\"sp-ea-one sp-easy-accordion\" data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\" data-offset-to-scroll=\"0\"><div class=\"ea-card ea-expand sp-ea-single\"><h3 class=\"ea-header\"><span class=\"ez-toc-section\" id=\"Is_clomipramine_still_used_for_OCD-2\"><\/span><a class=\"collapsed\" id=\"ea-header-643880\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse643880\" aria-controls=\"collapse643880\" href=\"#\" aria-expanded=\"true\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-minus\"><\/i> Is clomipramine still used for OCD?<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3><div class=\"sp-collapse spcollapse collapsed show\" id=\"collapse643880\" data-parent=\"#sp-ea-64388\" role=\"region\" aria-labelledby=\"ea-header-643880\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, although it is an outdated but effective medication utilized to treat this scenario.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><span class=\"ez-toc-section\" id=\"How_does_clomipramine_treat_Obsessive-Compulsive_Disorder\"><\/span><a class=\"collapsed\" id=\"ea-header-643881\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse643881\" aria-controls=\"collapse643881\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> How does clomipramine treat Obsessive-Compulsive Disorder?<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse643881\" data-parent=\"#sp-ea-64388\" role=\"region\" aria-labelledby=\"ea-header-643881\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">It works by:<\/span><\/p><ul><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Relaxing neurotransmitters, which are responsible for obsessions and compulsions.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Speed up the activity of Serotonin levels in the brain.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Relaxes the OCD loop or circuit activity.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Balances the intense emotions linked with OCD.<\/span><\/li><\/ul><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><span class=\"ez-toc-section\" id=\"Is_clomipramine_more_effective_than_SSRIs\"><\/span><a class=\"collapsed\" id=\"ea-header-643882\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse643882\" aria-controls=\"collapse643882\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is clomipramine more effective than SSRIs?<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse643882\" data-parent=\"#sp-ea-64388\" role=\"region\" aria-labelledby=\"ea-header-643882\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Although SSRIs are considered the latest medicines but clomipramine is often seen as more effective, but it has slightly higher side effects.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><span class=\"ez-toc-section\" id=\"When_are_the_effects_of_clomipramine_for_OCD_felt\"><\/span><a class=\"collapsed\" id=\"ea-header-643883\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse643883\" aria-controls=\"collapse643883\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> When are the effects of clomipramine for OCD felt?<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse643883\" data-parent=\"#sp-ea-64388\" role=\"region\" aria-labelledby=\"ea-header-643883\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Many individuals notice visible improvements within 4-6 weeks, while full effects require 8-12 weeks.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><span class=\"ez-toc-section\" id=\"Why_is_clomipramine_not_the_first_choice_for_OCD\"><\/span><a class=\"collapsed\" id=\"ea-header-643884\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse643884\" aria-controls=\"collapse643884\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Why is clomipramine not the first choice for OCD?<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse643884\" data-parent=\"#sp-ea-64388\" role=\"region\" aria-labelledby=\"ea-header-643884\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Doctors normally recommend the SSRIs first because clomipramine has a higher risk of side effects.<\/span><\/p><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Are you struggling with the overwhelming and intrusive thoughts? Do you want to consider clomipramine, but are afraid of it&#8230;<\/p>\n","protected":false},"author":9,"featured_media":64389,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[880],"tags":[932],"class_list":["post-64387","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-ocd-treatment"],"_links":{"self":[{"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/posts\/64387","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/comments?post=64387"}],"version-history":[{"count":0,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/posts\/64387\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/media\/64389"}],"wp:attachment":[{"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/media?parent=64387"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/categories?post=64387"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.royalclinicdubai.com\/en-ae\/wp-json\/wp\/v2\/tags?post=64387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}